St. John's will try to defy the odds as a No. 2 seed when the NCAA Tournament 2025 gets underway. Second-seeded teams have been upset by No. 15 seeds three times in the last four years, most recently with No.

Where the selection committee stumbled a bit: selecting North Carolina over more deserving teams like West Virginia. The Tar Heels snared the final at-large spot in the field despite going 1-12 in Quadrant 1 games and only defeating one at-large-caliber NCAA tournament team.