Insulin and its signaling systems are implicated in both central and peripheral mechanisms governing the ingestion, distribution, metabolism, and storage of nutrients in organisms ranging from ...

“Insulin is essential for life, but too much of it can also be deadly,” said Dr. Michael Karin, senior author of the study ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck ...

What is the difference between Type 1 and Type 2 diabetes? What about pre-diabetes? And how does insulin resistance factor in? Here's what to know.

Protein tyrosine phosphatase receptor type J (PTPRJ) is a negative regulator of insulin signaling in neuronal cells, according to a new study, and appears to have a role in nervous system development.

Brain Insulin in Worms and Flies: Biology Expanded. By 1997, molecules and signaling pathways homologous to the CNS insulin signaling system in mammals had been discovered in two very simple ...