Brock Purdy threw a one-yard TD to George Kittle that extended the San Francisco 49ers lead to 31-10 over the Tennessee ...

San Francisco 49ers quarterback Brock Purdy throws to tight end George Kittle who gains 24 yards against the Tennessee Titans ...

San Francisco 49ers quarterback Brock Purdy connects with tight end George Kittle on back-to-back plays against the Tennessee ...

The Titans found more success on their second drive, picking up 17 yards and a couple of first downs. They were in San ...

The 49ers scored on their first five possessions and seven of eight in the game, with only a fumble marring their streak.

Brandon Aiyuk’s time with the 49ers might be over. The wide receiver, who hasn’t played since he underwent right knee surgery ...

Brock Purdy threw three touchdown passes and the 49ers (10-4) cruised to a 37-24 win over the visiting Tennessee Titans (2-12 ...

San Francisco 49ers QB Brock Purdy's quick throw to TE George Kittle resulted in a 24-yard gain in the team's Week 15 matchup.

Brock Purdy threw three touchdown passes and the San Francisco 49ers started the stretch run of their season with a 37-24 ...

The Tennessee Titans aim for their third road victory of the season with a trip to the San Francisco 49ers on Dec. 14 in ...

The biggest news of the day comes in the health department, as three-time MVP Patrick Mahomes suffered a torn ACL late in the ...

The 49ers are didn't overwhelm the Titans in the first half, but they do lead 17-10 at halftime.San Francisco outgained ...