These two receptors can ... belong to a family of ligands—IGF1, IGF2, and insulin—that are highly homologous in structure and function. The IGFs can bind to six well-characterized soluble ...

The global Diabetes Drugs Market size was valued at USD 84.65 billion in 2024 and is expected to be worth around USD 177.74 ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Using protein structure prediction tools, researchers have uncovered receptor structure-function relationships to improve ...

The FDA has approved the first rapid-acting biosimilar insulin product for glycemic control ... on the potential of glucagon-like peptide-1 receptor agonists to address various health issues ...

The link between gut microbiome and eating behaviours, especially palatable food intake, is a growing focus of scientific ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...

Sliding scale insulin therapy involves following a chart of insulin dosages. A doctor will help a person with diabetes create this chart based on factors like how their body responds to insulin ...

Molecular communications in the bloodstream is a promising area of research, since the bloodstream has the ability to ...

Pattern recognition receptors (PRRs) are expressed by cells in the body in order to sense molecules that are associated with infection or tissue damage. They are important for activating the ...

When we compared the tissue exposure of the TLR7-TA99 ADC and an isotype control ADC, we found similar exposure in peripheral tissues, which could be attributed to the high dose level used for our ...