The addition of cimetidine 400 mg to metformin 250 mg resulted in a 50% increase in the plasma AUC of metformin and a 27% decrease in the 24-h renal excretion of metformin. [62] Because of the ...

Metformin, an oral medication used to treat type 2 diabetes, is often prescribed off-label for weight loss. It helps to control blood sugar by reducing both the amount of glucose produced by the ...