Can VCU be one of the 2025 March Madness bracket busters beginning with No. 6 seed BYU on Thursday? Before making any 2025 NCAA Tournament predictions, see the 2025 March Madness bracket picks from the proven computer model at SportsLine.

FILE – March Madness branding is displayed a Wilson EVO NXT basketball before a first-round college basketball game between Kent State and Notre Dame in the women’s NCAA Tournament Saturday March 23, 2024, in South Bend, Ind. (AP Photo/Michael Caterina, File)

The top-seeded Tigers will face No. 16 seed Alabama State on Thursday at 1:50 p.m. CT in Rupp Arena in Lexington, Kentucky. The Hornets earned the right to face Auburn by defeating St. Francis on Tuesday, 70-68. Alabama State secured the win thanks to an Amarr Knight layup with 0:01 remaining in the game.