The 2025 South Carolina football season is in full swing, with most teams having finished their season debuts. As the schedule continues, some of the state’s top squads will face each other in Week 2 of the current season.

College football Week 1 odds, picks, predictions, TV channel, streaming for Virginia Tech Hokies vs. South Carolina Gamecocks game on Sunday, Aug. 31.

The first full week of the 2025 regular season is here for South Carolina school football. Below is a look at this week’s top games in the Midlands and predictions for winners in Week 1: Players to Watch – C: WR Tylin Drakeford, DE, Dontrell Wilson; WK: RB Tiyon Fanning, WR Caleb Geronomi