Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet. Researchers have produced a comprehensive ...

On World Diabetes Day, pioneering physician-scientist E. Dale Abel reflects on a career spent uncovering how diabetes affects the heart and blood vessels. From uncovering the molecular mechanisms that ...

Researchers have produced a comprehensive picture of insulin signaling in mice and suggest that it is shaped by entangled effects of genetics and diet. The research, published today as a Reviewed ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, ...

In recent years, effective obesity treatments like Ozempic and Mounjaro have changed lives. These drugs mimic the effects of ...

Boston -- Fat cells that can't take up blood sugar normally appear to trigger the same problem in muscle and a related problem in liver, say researchers from Beth Israel Deaconess Medical Center in ...

Neurons like it tidy. Brain cells called glia help neurons perform at their best by cleaning up toxic cellular debris. But a diet high in sugar makes glia insulin resistant — which turns them into ...

Type 2 Diabetes is not just a disorder of glucose regulation but a visible marker of deep-seated metabolic chaos. By ...