Dopamine receptors bind dopamine, insulin receptors bind insulin ... which bind to signaling molecules outside the cell and subsequently transmit the signal through a sequence of molecular ...

Researchers from the German Diabetes Center (DDZ) and the Heinrich Heine University Düsseldorf (HHU) have studied the ...

Now, Boston Children's Division of Endocrinology researchers have discovered another purpose for BRD7: It seems to be involved in an alternative insulin signaling pathway, the existence of which ...

Why understanding the differences between Type 1 and Type 2 diabetes is essential for better health management and effective ...

Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2.

Using human endothelial cells, they found that ADM inhibited insulin receptor phosphorylation via protein-tyrosine phosphatase 1B, reducing insulin signaling. While becoming obese, these knockout ...

Discover how circulating cell-free DNA (cfDNA) is transforming the diagnosis and monitoring of metabolic diseases like ...

that likely operates upstream of the guanosine triphosphate (GTP)-binding G s protein in endothelial cells and its involvement in insulin signaling inhibition. To this end, small interfering ...

Fish oil supplementation altered the profile of defense cells, which switched from a pro-inflammatory to an anti-inflammatory state, reversing a condition similar to type 2 diabetes.