G protein-coupled receptor kinase 2 (GRK2) has emerged as a pivotal regulator in the pathophysiology of heart failure. GRK2 mediates the phosphorylation of activated G protein‐coupled receptors (GPCRs ...
St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors
St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford ...
Structure and the tethered activation mechanism of aGPCRs. (A) The basic structure of aGPCRs. This article highlights the critical role of mechanosensitive aGPCRs in human health and disease, setting ...
A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...
The discovery of G protein-coupled receptor (GPCR) heteromers has revealed a new level of complexity in their functional characteristics. This review explores a variety of methodologies and live cell ...
Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...
Up-to-date computational pipeline characterizes G-protein-coupled receptor (GPCR) repertoires in the closest relatives of metazoans, providing a framework to investigate the evolutionary origins and ...
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