VAN NUYS, CA — A chemical spill broke out at the Anheuser-Busch brewery in Van Nuys on Saturday afternoon, leading to an evacuation at the site, the Los Angeles Fire Department said in an alert.

A year before Disneyland opened, Anheuser-Busch opened a brewery in Van Nuys in 1954. Those grounds became the home of Busch Gardens, a 17-acre attraction that included manicured gardens ...