Ms. Psaki, 46, will host a show at 9 p.m. Tuesday through Friday, replacing Alex Wagner, a longtime political journalist who has anchored that hour since 2022, according to a memo to staff from Rebecca Kutler, MSNBC’s president. Ms. Wagner will remain at MSNBC as an on-air correspondent.

Media reports state the cable news network announced Monday that it would make major changes to its lineup, including making Psaki the anchor of the MSNBC's prime time 9 p.m. hour Tuesdays through Fridays. She will replace the former nightly prime time host Alex Wagner, who will remain with the network as a senior political analyst.

Joy Reid will exit MSNBC with the changes, while José Díaz-Balart and Katie Phang will also lose their dayside hours.