The San Francisco 49ers (9-4) will face the Tennessee Titans (2-11) in Week 15 at Levi’s Stadium, with all eyes on star running back Christian McCaffrey. McCaffrey was a late addition to the injury report on Saturday with a back issue, earning a questionable designation.

RB Christian McCaffrey is expected to play vs. the Titans despite a questionable tag, with multiple NFL insiders signaling good news.

The talk all off-season was that the 49ers play the worst division in football, but the NFC and the AFC South are ahead of the AFC North and NFC East in the standings. Before the year, you would have thought that the Ravens and Bengals would be much tougher than the Jaguars and Colts, but the records say differently.

The San Francisco 49ers could face a major setback when the 2025 NFL season ends, as Robert Saleh might be on a team's radar for head coach.

Need to know. Brock off a bye. 49ers quarterback Brock Purdy has played two games off a bye in his career, and he has been nearly perfect in both. In those two g

Before each NFL season, NFL media releases its list of top 100 players as voted on by NFL players.

As the 49ers return from their bye and host the Tennessee Titans, the fantasy landscape for this matchup looks very different from what it would have earlier in the season. Tennessee, meanwhile, is still searching for rhythm with a rookie quarterback and a reshaped skill-position group that no longer includes Derrick Henry or DeAndre Hopkins.

So if the Niners let him play out his contract, shake his hand, and watch him sign a solid $20-to-$30 (maybe $40) million-dollar deal elsewhere in free agency come the end of the 2026 season, the league office will essentially FedEx a third-round pick (fourth at worst) to Santa Clara. That’s money in the bank. That’s a free lottery ticket.